Uteroglobin : a Phospholipase A<SUB>2</SUB> Inhibitory Protein in Rabbit Blood
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چکیده
منابع مشابه
Glucocorticoid and developmental regulation of uteroglobin synthesis in rabbit lung.
The synthesis of uteroglobin in rabbit lung was studied after the administration of glucocorticoids to intact adult animals as well as during the late stages of rabbit development. The synthesis of uteroglobin was compared with levels of translatable uteroglobin mRNA in the lung. Uteroglobin synthesis was determined both by incorporation of [25S]methionine into the protein by lung explants incu...
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متن کاملGlucocorticoids induce the expression of the uteroglobin gene in rabbit foetal lung explants cultured in vitro.
In 27-day-old rabbit foetal lung explants cultured in vitro, the synthesis of the protein uteroglobin decreased progressively during several days of culture. Addition of glucocorticoids to the medium progressively induced the synthesis of uteroglobin in a dose-dependent manner without affecting the synthesis of total proteins. The glucocorticoid-mediated induction of uteroglobin appears mainly ...
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متن کاملUteroglobin gene expression in the rabbit uterus throughout gestation and in the fetal lung. Relationship between uteroglobin and eicosanoid levels in the developing fetal lung.
Uteroglobin (UG) gene encodes a cytokine-like, multifunctional, antiinflammatory protein, with potent phospholipase A2-inhibitory activity. It has been suggested that during implantation this protein protects the embryos from maternal immunological assault, facilitates the maintenance of quiescence in the uterus throughout pregnancy, prevents the onset of premature labor, and helps maintain an ...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1989
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.65.6_572